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Also used in some cases of heart failure

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Kensler and Eaton 2024), and its metabolites have been investigated for their suitability as biomarkers of exposure or effect in urine and blood

and Bifidobacterium spp

Research has demonstrated that celastrol induces paraptosis in breast cancer cells via the IP3R-dependent Ca 2+ signalling pathway, highlighting the critical role of Ca 2+ homeostasis disruption in this death pattern [124]